Directly from the Polyworks ReadMe.txt file:
09. I get this error when I try to run PolyWorks: System Error &H8007007E (-2147024770). The specified module could not be found. (Or any 'missing file' type errors.)
Make sure these files exist in your Windows\System32 folder: MBMouse.ocx, COMDLG32.OCX, mscomctl.ocx, msvbvm60.dll, dx8vb.dll, scrrun.dll. The first three are included in the PolyWorks zip, the others can be found with google. If putting them in the Windows\System32 folder doesn't work try registering the missing files: start -> run, type in regsvr32 name_of_file.dll_or_ocx.